Publications by authors named "R Fresco"

Article Synopsis
  • * They can be used to produce natural biocidal compounds that help control plant diseases, with their agricultural applications gaining interest despite a stronger focus on their pharmaceutical uses.
  • * This review discusses the various uses of macroalgae in agriculture, noting their potential as biofertilizers and plant growth enhancers, while also exploring their beneficial compounds like fatty acids and polyphenols that combat plant pathogens.
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Background: Ribociclib has been shown to have a significant overall survival benefit in patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer. Whether this benefit in advanced breast cancer extends to early breast cancer is unclear.

Methods: In this international, open-label, randomized, phase 3 trial, we randomly assigned patients with HR-positive, HER2-negative early breast cancer in a 1:1 ratio to receive ribociclib (at a dose of 400 mg per day for 3 weeks, followed by 1 week off, for 3 years) plus a nonsteroidal aromatase inhibitor (NSAI; letrozole at a dose of 2.

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Article Synopsis
  • Ribociclib has been shown to improve overall survival for patients with HR+/HER2- advanced breast cancer, and the NATALEE trial aims to evaluate its safety and effectiveness when combined with endocrine therapy for early nonmetastatic cases.* -
  • This Phase III trial involves a randomized, multicenter design, enrolling men and women with specific stages of breast cancer, and compares ribociclib with endocrine therapy alone, focusing on invasive disease-free survival as the main outcome.* -
  • The trial extends ribociclib treatment to 36 months to enhance effectiveness and uses a lower dosage to improve tolerability, including a diverse patient population for more comprehensive results on adjuvant therapy.*
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Purpose: The purpose of this study was to use qualitative methodology to better understand patient experiences after cubital tunnel surgery, with the goal of identifying areas of improvement in delivery of care.

Methods: Patients who underwent surgery (in situ decompression or anterior transposition) for cubital tunnel syndrome within the last 12 months, which was performed by one of three fellowship-trained hand surgeons, were identified. Participants were invited to an interview regarding "their experiences with ulnar nerve surgery.

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Background: Power Doppler ultrasonography has been used as an adjunct in the diagnosis of peripheral nerve compression neuropathy. To better characterize its sensitivity and specificity, the authors performed a systematic review of its use in carpal and cubital tunnel syndrome diagnosis.

Methods: The authors systematically reviewed published literature on the use of power Doppler ultrasound to diagnose peripheral compression neuropathy using Ovid MEDLINE, Embase.

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