The role of lipid droplets in microbial pathogenesis.

The nonpolar lipids present in cells are mainly triacylglycerols and steryl esters. When cells are provided with an abundance of nutrients, these storage lipids accumulate. As large quantities of nonpolar lipids cannot be integrated into membranes, they are isolated from the cytosolic environment in lipid droplets.

Plays a Role in Early Biofilm Formation, Interaction With and Virulence in .

The yeast exhibits multiple morphologies dependent on environmental cues. biofilms are frequently polymicrobial, enabling interspecies interaction through proximity and contact. The interaction between and the bacterium, , is antagonistic repressing the yeast-to-hyphal switch in .

Transcriptional response of Candida albicans to Pseudomonas aeruginosa in a polymicrobial biofilm.

Candida albicans is frequently co-isolated with the Gram-negative bacterium, Pseudomonas aeruginosa. In vitro, the interaction is complex, with both species influencing each other. Not only does the bacterium kill hyphal cells of C.

It's contrary - comorbidity does not affect survival of South Africans with colorectal cancer: An analysis from the Colorectal Cancer in South Africa cohort.

Background: The Colorectal Cancer South Africa (CRCSA) study is an observational cohort of patients with colorectal cancer (CRC) in Johannesburg, South Africa (SA). We found that the mean age at the time of CRC diagnosis was 56.6 years, consistent with studies from SA and sub-Saharan Africa.

Transcriptome Analyses of Biofilms, Exposed to Arachidonic Acid and Fluconazole, Indicates Potential Drug Targets.

is an opportunistic yeast pathogen within the human microbiota with significant medical importance because of its pathogenic potential. The yeast produces highly resistant biofilms, which are crucial for maintaining infections. Though antifungals are available, their effectiveness is dwindling due to resistance.