Publications by authors named "R Foster"

Canine mast cell tumours (MCTs) are one of the most common skin cancers of dogs. Surgical removal is the primary treatment, but recurrence and metastasis can occur even with low-grade tumours. As a result, new treatment strategies are being sought.

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Background: Peer workers are individuals who draw on their personal experiences in a professional capacity to support clients. Existing research on the role of peer workers in mental health, homelessness, and substance use services has primarily focused on their impact on client outcomes. This paper describes the development of peer workers as they transition into, through, and beyond this role.

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Article Synopsis
  • PIEZO1 is a membrane protein that forms trimeric, calcium-permeable channels, playing key roles in sensing mechanical forces across various cell types, including blood and stem cells, as well as tissues like bone and muscle.
  • This channel is being explored as a therapeutic target for a wide range of disorders, including cancers and cardiovascular issues, but research on its modulators is still in early stages.
  • Preliminary studies on small molecule agonists like the Yoda series show promise for developing new treatments and suggest potential for selective modulation of PIEZO1 to minimize side effects.
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