Publications by authors named "R Formisano"
Accelerated long-term forgetting: Design and validation of a neuropsychological tool in healthy subjects and diagnostic accuracy in a group of subjects with severe acquired brain injury.
Appl Neuropsychol Adult
January 2025
Article Synopsis
- The study investigates Accelerated Long-term Forgetting (ALF), highlighting that traditional memory tests often miss this phenomenon by only assessing retention shortly after learning.
- Experiment 1 involved healthy participants to develop a longer-term memory procedure that successfully captured long-term forgetting patterns, revealing a link between perceived memory function and actual performance.
- In Experiment 2, patients with severe Acquired Brain Injury demonstrated decreased memory retention over longer intervals compared to healthy participants, underscoring the necessity for extended memory assessments in clinical settings.
Article Synopsis
- - ApoE is a glycoprotein critical for lipid transport and metabolism, with the E4 allele being a known risk factor for Alzheimer's disease and potentially other neurological disorders like Parkinson's disease and brain trauma.
- - Recent findings suggest that the E4 allele is linked to worse clinical outcomes in various neurological conditions, mainly through its role in processes like amyloid-β accumulation and neuroinflammation.
- - This review aims to summarize the role of ApoE in neurodegenerative diseases and discuss the ethical considerations surrounding genetic testing for APOE variants, emphasizing its clinical significance.
Background/objectives: Terson Syndrome (TS) is a rare entity consisting of an intraocular hemorrhage secondary to subarachnoid hemorrhage (SAH) or intracerebral hemorrhage (IH). This study aimed to retrospectively describe the experience of the Ophthalmology Unit of Policlinico Gemelli, Rome, in the management of TS.
Methods: Twenty-four eyes of 19 patients (10 males-53%; 9 females-47%; mean age of 44.
Persons with disorders of consciousness (DoCs) may perceive pain without being able to communicate their discomfort. The Nociception Coma Scale (NCS) and its revised form (NCS-R) have been proposed to assess nociception in persons with DoCs. The main aim of this international multicenter study was to confirm (or not) our preliminary results and compare the NCS-R scores of standard stimulus (NCS-R-SS) to scores of personalized painful stimuli (NCS-R-PS).
View Article and Find Full Text PDFBiobanking, digital health and privacy: the choices of 1410 volunteers and neurological patients regarding limitations on use of data and biological samples, return of results and sharing.
BMC Med Ethics
September 2024
Article Synopsis
- The text discusses the ethical and legal considerations surrounding the collection of biological samples and data for research, especially in the context of neurological diseases and the role of biobanking.
- A study evaluated attitudes towards donating samples for biobanks among 1,454 participants, including healthy volunteers and patients with neurological conditions, with a high level of agreement on participation in biobanking.
- Key findings show significant differences in preferences regarding the return of results and data sharing, notably that healthy volunteers were more likely to want to remain uninformed about results compared to patients.