Publications by authors named "R Fleischmann"
Article Synopsis
- Multipin dry electrodes (dry EEG) offer a quicker and easier way to collect brain activity data compared to traditional wet EEG, making them suitable for research in neuropsychiatric disorders.
- The study involved 33 healthy participants and compared the performance of wet and dry EEG systems in measuring brain activity during resting states and specific tasks, using metrics like mismatch negativity (MMN) and connectivity measures.
- Results indicated that while dry EEG could reliably detect MMN and resting-state connectivity, it performed slightly worse in terms of amplitude and theta power, suggesting its potential utility despite differences in signal quality.
Article Synopsis
- This study looks at how doctors can figure out who might have memory problems after spine surgery in older patients, focusing on those 60 and up.
- They're using special tests before surgery, like brain scans and blood flow tests, to see if a certain measurement (the pulsatility index) can predict if someone will have issues like confusion after surgery.
- The results showed that about 1 in 5 patients had post-operative delirium, and older patients were more likely to experience it, with specific test scores helping to predict these problems.
No substantial neurocognitive impact of COVID-19 across ages and disease severity: a multicenter biomarker study of SARS-CoV-2 positive and negative adult and pediatric patients with acute respiratory tract infections.
Infection
October 2024
Background: Compared to intensive care unit patients with SARS-CoV-2 negative acute respiratory tract infections, patients with SARS-CoV-2 are supposed to develop more frequently and more severely neurologic sequelae. Delirium and subsequent neurocognitive deficits (NCD) have implications for patients' morbidity and mortality. However, the extent of brain injury during acute COVID-19 and subsequent NCD still remain largely unexplored.
View Article and Find Full Text PDFThe MHLC-C is a condition-specific instrument measuring the internal and external loci of control beliefs, adaptable to various health conditions. Translated into Swedish and Chinese, this study aims to translate the MHLC-C into German using the FACID-Method. The English version is validated and reliable; the German version requires these validation steps.
View Article and Find Full Text PDFObjective: To evaluate the efficacy and safety of upadacitinib over 5 years among patients with rheumatoid arthritis (RA) in a long-term extension (LTE) of the SELECT-BEYOND phase 3 trial.
Methods: Patients refractory to ≥1 biological disease-modifying antirheumatic drug (DMARD) received upadacitinib 15 mg or 30 mg once daily or placebo, in combination with background conventional synthetic DMARD(s). At week 12, patients randomised to placebo were switched to upadacitinib 15 mg or 30 mg.