Objective: The surgical treatment of claudication can be associated with significant morbidity and costs. There are growing concerns that some patients proceed to interventions without first attempting evidence-based nonoperative management. We used a direct, cross-site, blinded expert review to evaluate the appropriateness of the surgical treatment of claudication.
View Article and Find Full Text PDFJ Exp Psychol Hum Percept Perform
October 2007
Previous research suggests that motor equivalence is achieved through reliance on effector-independent spatiotemporal forms. Here the authors report a series of experiments investigating the role of such forms in the production of movement sequences. Participants were asked to complete series of arm movements in time with a metronome and, on some trials, with an obstacle between 1 or more of the target pairs.
View Article and Find Full Text PDF1. A single dose of pentazocine induces cross-tolerance the analgesic effects of the kappa agonist U 50488H. Tolerance is observed by means of the hot plate test or by the i.
View Article and Find Full Text PDFComp Biochem Physiol C Comp Pharmacol Toxicol
February 1992
1. The chronic toxicity of pentachlorophenol (PCP) was studied in rats after 90-120 days of oral administration ad libitum of 0.3-3 mM PCP aqueous solutions.
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