Artificial Intelligence in Cutaneous Leishmaniasis Diagnosis: Current Developments and Future Perspectives.

Cutaneous Leishmaniasis (CL) is a major global health problem requiring appropriate diagnosis methods. Its diagnosis is challenging, particularly in resource-limited settings. The integration of Artificial Intelligence (AI) into medical diagnostics has shown promising results in various fields, including dermatology.

Intramyocellular lipid variations in active older men: relationship with aerobic fitness.

Aims: Intramyocellular lipid (IMCL) variations in older men are poorly explored. In young adults, IMCL can be influenced by both diet and exercise interventions; this flexibility is related to aerobic fitness. We evaluated in active older adults the influence of maximal aerobic capacity on short-term diet and exercise-induced variations in IMCL stores.

In vivo assessment of mouse hindleg intramyocellular lipids by 1H-MR spectroscopy.

Rationale And Objectives: (1)H-magnetic resonance spectroscopy ((1)H-MRS) has proved to be the sole in vivo technique able to measure intramyocellular lipids (IMCL) in both humans and animals. Mouse models are now widely used for physiologic studies and drug discovery. However, IMCL assessment using (1)H-MRS is hindered in this animal model by the small muscle size and strong contamination from the extramyocellular lipid (EMCL) signal.

Measurement of nonlinear pO2 decay in mouse lungs using 3He-MRI.

Spatial and temporal variations in oxygen partial pressure (pO(2)) during breath-hold can be exploited to obtain important regional parameters of lung function. In the course of apnea, the oxygen concentration is known to decay exponentially. Therefore, the initial pO(2) (p(0)) can be used to represent local ventilation, and the oxygen depletion time constant can characterize perfusion.