Publications by authors named "R Figueira"
Disruption of developmental processes affecting the fetal lung leads to pulmonary hypoplasia. Pulmonary hypoplasia results from several conditions including congenital diaphragmatic hernia (CDH) and oligohydramnios. Both entities have high morbidity and mortality, and no effective therapy that fully restores normal lung development.
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- Knowledge of the Cerithiopsidae family in Brazil is minimal, prompting a study to confirm the occurrence of various species through extensive research of malacological collections.
- The study confirms the presence of several species, provides new insights on their distribution and shell morphology, and rejects the occurrence of some others in Brazil.
- Additionally, nine new species are proposed, while some existing species are reclassified or considered synonyms, reflecting a more accurate understanding of this mollusc group's diversity in the region.
Background of persistent organic pollutants in estuarine sediments from the Marajó Island, an Amazonian environmental protection area for sustainable use.
Environ Sci Pollut Res Int
December 2024
Marajó Island, an environmental protection area for sustainable use in the Brazilian Amazon, was the first region in Brazil to apply the pesticide DDT, a persistent organic pollutant (POP), to control malaria outbreaks. This study investigated background levels of various POPs, including o,p'- and p,p'-DDT and their primary metabolites (o,p'- and p,p'-DDE, o,p'- and p,p'-DDD), as well as hexachlorocyclohexane (α-, β-, γ-, δ-HCH), using estuarine surface sediments and sediment cores from areas influenced by urbanization and agriculture. All samples were collected during the dry season (September 2014).
View Article and Find Full Text PDFOligohydramnios (decreased amniotic fluid volume for gestational age) is a severe condition associated with high morbidity and mortality mainly due to fetal pulmonary hypoplasia. Currently, there are limited treatment options to promote fetal lung development. Administration of stem cells and their derivates have shown promising regenerative properties for several fetal and neonatal diseases related to arrested lung development.
View Article and Find Full Text PDFPurpose: Amniotic fluid stem cell extracellular vesicles (AFSC-EVs) hold regenerative potential to treat hypoplastic lungs secondary to congenital diaphragmatic hernia (CDH). This study aims to investigate sex-specific differences in pulmonary hypoplasia severity and responses to AFSC-EV administration in an experimental CDH mouse model.
Methods: C57BL/6J dams were fed with nitrofen + bisdiamine (left-sided CDH) or olive oil only (control) at embryonic day (E) 8.