Publications by authors named "R Fernando Cantor"

The 15th Annual Report from The Society of Thoracic Surgeons Interagency Registry for Mechanically Assisted Circulatory Support includes 29,634 continuous-flow left ventricular assist devices from the 10-year period between 2014 and 2024. The outcomes reported here demonstrate continued improved survival in the current era of fully magnetically levitated devices, with a significantly higher 1-year (85.7% vs 78.

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  • Arrhythmias can cause severe heart issues in children, and when they are severe, heart transplantation (HTX) may be necessary, but this group has not been distinctively studied.
  • *This study aimed to look at pediatric patients who needed HTX primarily due to malignant arrhythmia (MA) and how their outcomes compared to others on the list.
  • *Out of thousands listed for HTX, only 63 patients (1.4%) had MA as the reason; although they were generally older and more likely to have had cardiac arrests, their chances of surviving and recovering after transplantation were similar to those without MA.
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  • - This study examined the incidence and risk factors for early stroke within the first week after the implantation of a left ventricular assist device (LVAD), revealing that 5.9% of patients experienced a stroke, with about half occurring in the initial 7 days post-surgery.
  • - Key findings indicated that older age, having a temporary mechanical circulatory support (MCS) device, being of white race, and the presence of a left atrial clot before surgery were all associated with a higher risk of early stroke.
  • - The study highlights the need for ongoing risk assessment and improvement strategies in the management of patients undergoing LVAD implantation to reduce early stroke occurrences.
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Background: Studies evaluating the prevalence and impact of recurrent rejection (RR) in pediatric heart transplant (HT) are sparse.

Objectives: The purpose of this study was to describe prevalence and impact of RR on cardiac allograft vasculopathy (CAV) and graft loss after pediatric HT.

Methods: Data on HT from January 1, 2000, to June 30, 2020, in the Pediatric Heart Transplant Society database were included.

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Article Synopsis
  • The study investigates the use of mechanical circulatory support (MCS) in pediatric heart transplant patients, focusing on incidence, contributing factors, and outcomes based on a large database from 2010-2020.
  • Among 4,321 primary heart transplants analyzed, 5.8% (249 patients) required MCS, with factors like congenital heart disease and older donor age linked to higher MCS need, while larger recipient size and better donor heart function correlated with lower needs.
  • The one-year survival rate for patients requiring MCS was significantly lower at 54.2% compared to 94.8% for those without, but those who survived the first year had favorable long-term outcomes, suggesting selective use of MCS
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