Publications by authors named "R Fernandez-Durango"
Purpose: MicroRNA (miR) expression in endothelial progenitor cells (EPCs) in type 1 diabetes (DM1) and its relation with different stages of diabetic retinopathy (DR) have not been reported to date. Our aim was to analyze miR-222, miR-221, and miR-126 expression in EPCs from DM1 patients with and without DR.
Methods: We included 41 patients with DR, 35 without DR, and 38 controls.
Purpose: To analyze if endothelin 1 may have an effect on central retinal artery (CRA) blood flow velocities and intraocular pressure (IOP) in retinal detachment.
Methods: Using radioimmunoassay, immunoreactive endothelin 1 levels were tested in both plasma and subretinal fluid specimens from patients with retinal detachment, while only plasma specimens from healthy subjects were tested. Central retinal artery Doppler sonography parameters and IOP were measured in eyes with retinal detachment, with and without proliferative vitreoretinopathy, their respective healthy fellow eyes, and normal eyes.
Aims: The purpose of this study is to investigate circulating endothelial progenitor cells (EPCs) and the signaling pathways involved in their recruitment in the ischemic retina of the 50/10 rat model of oxygen-induced retinopathy (OIR).
Main Methods: Within 12h after birth, litters of Sprague-Dawley rats and their mothers were exposed to alternating oxygen concentrations, followed by a room air exposition, to induce OIR. Retinopathy was quantified by ADPase stain in flat-mounted retinas and pre-ILM nuclei count in retinal sections.
Purpose: To find models that will explain the variability in postoperative visual acuity (VA) (logarithmic: logMAR) associated with unilateral primary rhegmatogenous retinal detachment (RD).
Methods: This was a prospective clinical cohort study of 33 patients with proliferative vitreoretinopathy (PVR: PVR