Publications by authors named "R Fernandez Espino"
Article Synopsis
- The study investigates the impact of gonadotropin-releasing hormone analogues (GnRHa) on adult height in girls with idiopathic central precocious puberty (CPP), a condition that can hinder growth.
- The research involved data from 465 girls diagnosed with idiopathic CPP across 55 centers in Spain from 1998 to 2012, assessing their growth and development while undergoing treatment.
- Findings indicate that GnRHa treatment can help maintain genetic growth potential, with results showing a slight difference between achieved adult height and target height, suggesting some benefit in height preservation.
African swine fever (ASF) is a contagious hemorrhagic disease affecting both domestic and wild pigs with high mortality rate and severe socio-economic losses. Due to the virus' potential ability to remain infectious in suitable conditions and environments, it is imperative to identify risk factors that may contribute to its transmission. The Philippines' current ASF surveillance relies on pig blood samples.
View Article and Find Full Text PDFObjectives: Since low insulin-like growth factor (IGF) 1 is often linked to inflammation, we analyze whether serum levels of IGF1 are associated with cardiovascular disease (CVD) in rheumatoid arthritis (RA) in a longitudinal observational study.
Methods: A CVD risk was estimated (eCVR) in 184 female RA patients (mean age 52 years) and in 132 female patients after ischemic stroke (mean age 56 years) with no rheumatic disease, using the Framingham algorithm. The median level of IGF1 divided the cohorts in IGF1 and IGF1 groups.
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency is an autosomal recessive disorder caused by mutations in the CYP21A2 gene. Cortisol and aldosterone synthesis are impaired in the classic forms (adrenal insufficiency and salt-wasting crisis). Females affected are virilised at birth, and are at risk for genital ambiguity.
View Article and Find Full Text PDFBackground: The influence of gonadotropin-releasing hormone analogue (GnRHa) treatment on body mass index (BMI) evolution in girls with idiopathic central precocious puberty (CPP) is unclear. Hence, we aimed to evaluate the effect of GnRHa treatment on BMI-standard deviation score (SDS) from diagnosis of idiopathic CPP until adult height.
Methods: An observational study of girls diagnosed with CPP in Spain was carried out between January 2008 and December 2014.