Publications by authors named "R Feenstra"

Article Synopsis
  • The study evaluates how well epicardial vasomotion and coronary blood flow (CBF) alone can diagnose coronary endothelial dysfunction (CED) in patients with angina and non-obstructive coronary arteries.
  • It involved 110 patients undergoing coronary function testing, finding that using epicardial diameter or CBF alone missed significant instances of CED diagnoses.
  • The conclusion emphasizes that both parameters are necessary for a comprehensive diagnosis of CED to avoid missing cases related to microvascular and epicardial issues.
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Article Synopsis
  • * A case study of four VSA patients revealed that all experienced significant coronary vasoconstriction during acetylcholine testing, but their ECGs differed between spontaneous episodes and induced spasms in three out of four cases.
  • * The findings indicate that the ECG during spontaneous VSA episodes may not match those seen during acetylcholine-induced spasms, emphasizing the need for ECG monitoring during spontaneous angina to improve diagnosis
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Coronary endothelial dysfunction (CED) and coronary artery spasm (CAS) are causes of angina with no obstructive coronary arteries in patients. Both can be diagnosed by invasive coronary function testing (ICFT) using acetylcholine (ACh). This study aimed to evaluate the diagnostic yield of a 3-minute ACh infusion as compared with a 1-minute ACh bolus injection protocol in testing CED and CAS.

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Recently, a novel method to estimate wedge pressure (P)-corrected minimal microvascular resistance (MR) was introduced. However, this method has not been validated since, and there are some theoretical concerns regarding the impact of different physiological conditions on the derivation of P measurements. This study sought to validate the recently introduced method to estimate P-corrected MR in a Doppler-derived study population and to evaluate the impact of different physiological conditions on the P measurements and the derivation of P-corrected MR.

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