The Submental Artery Island Flap for Reconstruction of Acquired Maxillary and Palatal Defects After Tumor Ablation: Reversed Flow Versus the Extended Antegrade Design.

Background: The submental artery island flap (SIF) is a valid option for palatal reconstruction. However, the main limitation for its application for palatal defects is the arc of rotation. A novel modification for tunneling of the antegrade design of SIF that allows a compliant easy reach to the defect is described.

Burden of congenital and hereditary anomalies in the population of Azad Jammu and Kashmir, Pakistan.

Objectives: This study was aimed to elucidate the prevalence-pattern of congenital and hereditary anomalies (CA) in the population of Azad Jammu and Kashmir (AJK), which is a logistically difficult area in the north-east of Pakistan and in the foot-hills of Himalayas.

Method: A cross-sectional clinico-epidemiological study was carried out during 2018-2020 in three districts of AJK and individuals/families with CA were recruited from hospitals, public places and through door-to-door surveys. The anomalies were classified with the help of specialized clinicians and their definitions were sought from OMIM and ICD-10 databases.

Modification of natural compounds through biotransformation process by microorganisms and their pharmacological properties.

The biotransformation of natural compounds by fungal microorganisms is a complex biochemical process. Tandem whole-cell biotransformation offers a promising, alternative, and cost-effective method for modifying of bioactive novel compounds. This approach is particularly beneficial for structurally complex natural products that are difficult to be synthesized through traditional synthetic methods.

Evaluation of case based simulation teaching to improve the Family Medicine residents urgent care management skills at a teaching hospital.

Context: Simulation based teaching is effective strategy to allow trainees to acquire skills, develop clinical judgment and to become competent in order to manage the patients in a safe environment. The Case-based simulation improves the assessment and management skills of the trainees to prepare them as a competent physician.

Aim: Evaluation of case based simulation teaching to improve the Family Medicine residents urgent care management skills at a teaching hospital.

Comparative effectiveness of oblique lumbar interbody fusion with anterior screw fixation versus percutaneous pedicle screw fixation for treating lumbar degenerative diseases: A systematic review and meta-analysis.

Purpose: Lumbar degenerative diseases impose a substantial health burden, prompting the exploration of advanced surgical approaches such as Oblique Lumbar Interbody Fusion (OLIF). This meta-analysis aims to evaluate the comparative efficacy of OLIF with anterior screw fixation (OLIF-AF) against OLIF with posterior pedicle fixation (OLIF-PF) in addressing these conditions.

Methods: A systematic search across multiple databases identified five studies meeting inclusion criteria, incorporating a total of 271 patients.