Publications by authors named "R Fadic"
Objectives: The sympathetic skin response (SSR) is a well-established test, whereas the electrochemical skin conductance (ESC) is still under evaluation. Our aim was therefore to assess the diagnostic accuracy of ESC to detect abnormal sudomotor function, using SSR as a reference test.
Methods: A cross sectional observational study was performed of 61 neurological patients assessed for possible sudomotor dysfunction and 50 age-matched healthy controls (HC).
Article Synopsis
- * Detailed clinical assessments, including nerve conduction studies and skin biopsies, revealed reduced nerve fiber density in the lower legs but no significant abnormalities in other tests.
- * Symptoms persisted for several months in two patients, highlighting a rare but serious adverse effect linked to the vaccination.
Background: The International Classification of Headache Disorders lists different subtypes of medication overuse headache (MOH), according to the medication overused. The aim of this study is to evaluate whether the different subtypes correspond to clinically distinguishable phenotypes in a large population.
Method: This descriptive cross-sectional observational study included 660 patients with MOH referred to headache centers in Europe and Latin America as a part of the COMOESTAS project.
Measles is still a major cause of child morbidity and mortality. In recent years, it has become a global public health problem, attributed to low vaccination coverage observed in different countries. In order to control it, a highly effective live virus vaccine is available, which was used for the first time in Chile in 1964, covering practically the whole country in a short period of time.
View Article and Find Full Text PDFBackground: Medication-overuse headache is a costly disease for individuals and society.
Objective: To estimate the impact of medication-overuse headache treatment on direct and indirect headache-related health care costs.
Methods: This prospective longitudinal study was part of the COMOESTAS project (COntinuous MOnitoring of Medication Overuse Headache in Europe and Latin America: development and STAndardization of an Alert and decision support System).