Publications by authors named "R F Viggers"
Article Synopsis
- Individuals with type 1 diabetes (T1D) have an increased risk of fractures, prompting the American Diabetes Association to incorporate bone health assessments into their 2024 Standards of Care.
- A study compared bone mechanical properties and microstructure between 111 individuals with T1D and 37 healthy controls using various imaging techniques to assess bone health.
- Results showed no significant difference in bone mineral density (BMD) between the T1D and control groups, indicating that further research is needed to establish a distinct bone health profile for those with T1D.
Fracture risk revisited: Bone mineral density T-score and fracture risk in type 2 diabetes.
Diabetes Obes Metab
November 2024
Aim: To study the association between femoral neck (FN) bone mineral density (BMD) T-score and fracture risk in individuals with and without type 2 diabetes (T2D).
Materials And Methods: We performed a single-centre retrospective cohort study using the Danish National Health Service. BMD of the FN was measured by dual-energy X-ray absorptiometry.
Aim: To determine the association of diabetes-related characteristics with fractures at different sites in individuals with type 2 diabetes (T2D).
Materials And Methods: We conducted a cohort study using the Clinical Practice Research Datalink (CPRD) GOLD. Patients aged over 30 years with T2D were identified within the CPRD.
Type 2 diabetes (T2D) is a prevalent disease and has been associated with an increased fracture risk despite normal or even higher areal BMD. The aim of this study was to estimate the association between glucose metabolism status (GMS) and measurements of glycemic control with HRpQCT parameters of bone microarchitecture and strength. Participants of the Maastricht study who underwent an HRpQCT scan at the distal radius and tibia were included.
View Article and Find Full Text PDFPurpose: Osteoglycin is hypothesized to be metabolically active and may enhance insulin action. We hypothesized that osteoglycin levels increase during hyperglycemia as a physiological response to enhance the effects of insulin.
Methods: Eight healthy males were included in a cross-over study consisting of three study days following an 8 h fast.