Publications by authors named "R F Valenzuela"
A new antioxidant lipid (AL) was synthesized from rainbow trout () belly oil and cold-pressed maqui (CPM) ( (Mol.) Stuntz) seed oil via enzymatic interesterification using in supercritical CO medium. A Box-Behnken design with 15 experiments was employed, with the independent variables being the following: belly oil/CPM oil ratio (10/90, 50/50, and 90/10, /), supercritical CO temperature (40.
View Article and Find Full Text PDFThe family Hypoxylaceae has a cosmopolitan distribution with greater diversity in tropical regions, its growth habit is saprotrophic, endophytic and potentially phytopathogenic. From the revision of herbarium specimens and field collections from the Yucatan Peninsula, two new species were described: , characterized by having fusiform spores and which is distinguished by having stromata vinaceous and dark brown KOH-extractable pigments. The species are described based on morphological characters and Bayesian Inference analyses of four molecular markers (ITS, LSU, RPB2 and TUB2).
View Article and Find Full Text PDFObjective: Obesity is associated with liver depletion of ω-3 polyunsaturated fatty acids (ω-3 PUFAS) promoting steatosis and inflammation, whose levels are maintained by diet or biosynthesis involving Δ-5D, Δ-6D desaturases and elongases.
Method: We aimed to assess Δ-5D and Δ-6D activities in liver and brain from mice fed a control diet (CD) or high-fat diet (HFD) for four to sixteen weeks.
Results: HFD led to (1) an early (4 weeks) enhancement in liver Δ-5D, Δ-6D, and PPAR-α activities, without changes in oxidative stress, liver damage or fat accumulation; (2) a latter progressive loss in hepatic desaturation with insufficient compensatory increases in mRNA and protein expression, leading to ω-3 PUFA depletion, PPAR-α down-regulation reducing FA oxidation, and liver steatosis with enhancement in lipogenesis; and (3) brain ω-3 PUFA depletion after 12 to 16 weeks of HFD feeding.
Article Synopsis
- The Border Coalition for Fitness (BCF) is a partnership focused on increasing physical activity in El Paso, Texas, through walking challenges and community engagement.
- A mixed-methods evaluation highlighted that BCF members rated their leadership, resources, and commitment to organizing actions significantly higher than team captains or community participants.
- Although the BCF was seen as effective in its programming and community impact, participants suggested improvements in recruiting and retaining members, advocating for greater inclusion of community members and walking challenge participants.
Cold-Pressed (Mol.) Stuntz Seed Oil Prevents Metabolic-Dysfunction-Associated Steatotic Liver Disease (MASLD) in a High-Fat-Diet-Induced Obesity Murine Model.
Antioxidants (Basel)
November 2024
Article Synopsis
- * Four groups of male C57BL/6 mice were supplemented with either control diet or HFD, with either sunflower oil or maqui oil, over a 12-week period.
- * Results showed that MO supplementation led to significant reductions in visceral fat, liver fat infiltration, and certain liver enzyme levels, indicating its potential to combat fatty liver disease and suggesting further research for human health applications.