[The physical development of children of school age (7-17 years) in the Kirghiz Republic].

The article presents the results of comparative analysis of indices of physical development of school-age children residing in various regions of the Republic of Kyrgyzstan. The statistically significant relationship between body length and body mass of examined children from territories of their residence was established. The children from Bishkek had significantly higher values as compared to children from villages of highlands and the south and the north of the country as well.

New mutation in WT1 gene in a boy with an incomplete form of Denys-Drash syndrome: A CARE-compliant case report.

Rationale: Pediatric patients with WTl-associated syndromes (including Wilms' tumor-aniridia syndrome and Denys-Drash syndrome), Perlman syndrome, mosaic aneuploidy, and Fanconi anemia with a biallelic breast cancer type 2 susceptibility protein mutation have the highest risk of developing Wilms' tumor.

Patient Concerns And Diagnosis: We describe a patient with bilateral metachronous Wilms' tumor, ambiguous genitalia characterized by 46, XY disorder of sexual development (DSD) with scrotal hypospadias and bilateral abdominal cryptorchidism, but without nephropathy. At the age of 7 months, the child underwent left nephrectomy with left orchiopexy.

[The Modern Medical Technologies in Orphan Diseases Prevention].

The article covers issues of organization of orphan diseases prevention using modern technologies. The role of preconception training, medical genetic counseling, auxiliary reproductive technologies, prenatal diagnostic and fetal surgery techniques, neonatal screening at particular stages of preventive measures is reflected.

[The regional model of three-level system of of medical social monitoring of children and adolescents: the pilot project in the Republic of Tatarstan].

The absence of system of medical social monitoring of children being in difficult life situations is one of main causes of preventable losses of health and life of children and adolescents. The plan of activities of the working group No3 under the Coordination council under the President of the Russian Federation of the national strategy realization of actions in interest of children for 2012-2017 includes a point: "The development and implementation of standard model of medical social monitoring of children and adolescents in the subjects of the Russian Federation". The implementation of this task is assigned to the Department of social pediatrics of The research center of children health of Moscow and the Ministry of Health of the Republic of Tatarstan.