Application of an ultraviolet (UV) spectroscopic method for measuring lipoprotein cholesterol in diabetic hypothyroid rats.

Methods for the isolation and quantitation of cholesterol involve time-consuming chromatographic procedures coupled with the development and measurement of color complexes. The intensity of most color complexes varies with time. This study was undertaken to develop a UV spectrophotometric method to measure cholesterol concentration in plasma lipoprotein fractions.

Research centers on minority institutions (RCMI): II.

The goal of the Research Centers in Minority Institutions (RCMI) is to develop biomedical and behavioral research at institutions with 50% minority enrollment (African Americans, Hispanics, Native Hawaiians, Pacific Islanders, Native Americans and Alaska Natives) who have been underrepresented in the biomedical sciences. The program has made available resources vital to scientific development and progress. While these resources have included, equipment, personnel supplies, Core laboratories etc, important effective approaches to research also have been emerging.

The effect of regular alcohol use on the management of non-insulin diabetes mellitus.

This is a retrospective study, in which we investigated the impact of regular alcohol use on the clinical management of non-insulin dependent diabetes mellitus (NIDDM) patients from the outpatient clinic of the VA Medical Center in New Orleans, Louisiana. The study population included randomly selected NIDDM patients of which 40% used alcohol regularly. The fasting blood sugar (FBS) in non-users of alcohol stayed in the "normal" (< or = 140 mg/dl) and "acceptable " (< or = 175 mg/dl) range and that of regular users of alcohol remained at the "fair" (< or = 235 mg/dl) and "poor" (> 235 mg/dl) range.

Research Centers in Minority Institutions (RCMI).

The Research Centers in Minority Institutions (RCMI) Program was initiated in the United States of America in 1985 as a congressionally mandated program. The mission of the RCMI Program is to expand the national capacity for the conduct of biomedical and behavioral research by developing the research infrastructure at institutions granting doctoral degrees in health or health-related sciences, that have 50% or greater enrollment of minorities (African Americans, Hispanics, Native Hawaiians and Pacific Islanders, Native Americans and Alaska Natives) that are underrepresented in the biomedical sciences. The program administration is based in the National Center for Research Resources (NCRR), at the National Institutes of Health (NIH), an agency of the Department of Health and Human Services (DHHS).

Evidence for the interaction of protein kinase C and melanocortin 3-receptor signaling pathways.

The melanocortin-3 receptor, MC3-R, is abundant in the brain and is activated by gamma-2-melanocyte stimulating hormone (gamma-2-MSH). We have previously reported the translocation of protein kinase C (PKC) in spontaneous hypertensive rat (SHR) brain synaptosomes treated with gamma-2-MSH. In this study, the expression of PKA and the related PKB in SHR brain synaptosomes was analyzed.