Publications by authors named "R F Neuteboom"
Article Synopsis
- Neuroaxonal loss may begin early in multiple sclerosis (MS), but it's unclear if this is due to inflammation or neurodegeneration related to genetics and environment during childhood.
- A study analyzed the impact of genetic risk scores and childhood environmental factors, like Epstein-Barr virus exposure and parental smoking, on brain MRI outcomes in children aged 9 and 13.
- Findings suggest that genetic predisposition and exposure to parental smoking can reduce brain volumes, indicating potential strategies for early MS prevention in at-risk individuals.
Background And Objectives: Anti-NMDA receptor (anti-NMDAR) encephalitis generally manifests in young adults. Although 80%-90% returns to independence, the majority experience persistent cognitive and psychosocial difficulties. Studies have demonstrated that cognitive recovery may continue for years; the temporal trajectory is largely unknown, as are factors influencing cognitive/psychosocial recovery.
View Article and Find Full Text PDFBackground And Objectives: Autoimmune encephalitis (AIE) and paraneoplastic neurologic syndromes (PNSs) encompass a heterogeneous group of antibody-associated disorders. Both the number of syndromes and commercially available antibody tests have increased considerably over the past decade. High-quality population-based data on epidemiology of these disorders and real-world performance of antibody tests are needed.
View Article and Find Full Text PDFLong-term follow-up MR imaging in children with transverse myelitis.
Mult Scler Relat Disord
December 2024
Article Synopsis
- The study investigates how lesions in children with transverse myelitis (TM) resolve over time, focusing on different related diseases: MOG-antibody associated disorders (MOGAD), multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD), and double seronegative TM.
- A total of 78 children from various medical centers were assessed, and a grading system was used to measure the resolution of lesions over time.
- Results showed that MOGAD had the fastest and most complete resolution of lesions, followed by double seronegative TM, MS, and NMOSD, with none of the NMOSD patients achieving complete resolution during the observation period.
The importance of long term follow-up in children with acquired demyelinating syndromes.
Eur J Paediatr Neurol
September 2024