Publications by authors named "R F Massung"

Q-fever is an underreported disease caused by the bacterium , which is highly infectious and has the ability to disperse great distances. It is a completely clonal pathogen with low genetic diversity and requires whole-genome analysis to identify discriminating features among closely related isolates. , and in particular one genotype (ST20), is commonly found in cow's milk across the entire dairy industry of the USA.

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Article Synopsis
  • A study in Bangladesh aimed to identify infections from Rickettsia, Coxiella, Leptospira, Bartonella, and Chikungunya virus in patients with fever who visited hospitals between December 2008 and November 2009.
  • Out of 720 patients tested, 37% were found to be infected with Rickettsia, with specific cases linked to different types such as spotted fever and scrub typhus.
  • The findings suggest that rickettsial infections are common but often overlooked, highlighting the need for updated clinical guidelines to improve diagnosis and treatment.
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In August 2012, laboratory tests confirmed a mixed outbreak of epidemic typhus fever and trench fever in a male youth rehabilitation center in western Rwanda. Seventy-six suspected cases and 118 controls were enrolled into an unmatched case-control study to identify risk factors for symptomatic illness during the outbreak. A suspected case was fever or history of fever, from April 2012, in a resident of the rehabilitation center.

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Coxiella burnetii is a gram-negative bacterium that is the etiologic agent of the zoonotic disease Q fever. Common reservoirs of C. burnetii include sheep, goats, and cattle.

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Article Synopsis
  • Tickborne rickettsial diseases pose serious health risks to both adults and children, requiring early recognition for effective treatment.
  • Despite the availability of low-cost antibiotics like doxycycline, the nonspecific early symptoms complicate diagnosis.
  • The CDC has updated guidelines for healthcare professionals regarding recognition, treatment, and reporting of these diseases, including new rickettsial agents identified since 2004.
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