Publications by authors named "R F Harvey"
Background: Alzheimer's disease (AD) manifests with early spatial memory impairment and is linked to the degeneration of hippocampal circuits. Hippocampal sharp wave ripples (SWRs) are high-frequency population-burst events that coordinate the reactivation of neural assemblies (groups of neurons that become correlated in their firing patterns during learning) in post-learning sleep, which is the neural basis of memory consolidation. SWRs are reduced in the APP/PS1 mouse model of AD-like pathology.
View Article and Find Full Text PDFIntroduction: Detrusor contractions can be classified as either volitional or involuntary. The latter are a hallmark of urge urinary incontinence. Understanding differences in neuroactivation associated with both types of contractions can help elucidate pathophysiology and therapeutic targets.
View Article and Find Full Text PDFBackground: The goal of this FDA-committed, post authorization study was to assess the real-world effectiveness of Ad26.COV2.S in preventing observed COVID-19 disease in individuals in the United States interacting with the healthcare system who were vaccinated according to the national immunization recommendations.
View Article and Find Full Text PDFArticle Synopsis
- Radiomics involves extracting features from medical imaging data to enhance clinical applications, especially in rhinology where CT imaging of the paranasal sinus is crucial for diagnosis and treatment assessment.
- A systematic review analyzed techniques for radiomic data derived from CT scans, resulting in 10 eligible studies categorized into diagnostics and prognostics, using various extraction methods and analytical approaches.
- While the potential of radiomics in rhinology is promising, the current studies show variable quality and limited clinical applicability, indicating a need for more robust research in this area.