Publications by authors named "R F Geddes"

Article Synopsis
  • This study investigates the impact of a magnesium-enriched diet on cats with chronic kidney disease (CKD), focusing on its potential to improve plasma magnesium levels and overall health outcomes.* -
  • Sixty client-owned cats with CKD were randomly split into two groups: one received a magnesium-enriched phosphate-restricted diet (PRD), while the other received a standard PRD. Results showed an increase in total magnesium in the magnesium group without negative side effects.* -
  • The magnesium-enriched diet led to better management of CKD-related issues, such as lower trends in ionized calcium levels and stable fibroblast growth factor-23 concentrations, suggesting this dietary modification could be beneficial for feline patients with CKD.*
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Background: Microscopic nephrocalcinosis is a common pathological feature of chronic kidney disease (CKD) in cats. Detection of macroscopic nephrocalcinosis using ultrasonography and its implications remain unexplored.

Objectives: Identify risk factors associated with ultrasound-diagnosed nephrocalcinosis and evaluate the influence of nephrocalcinosis on CKD progression.

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Article Synopsis
  • This study investigates how effectively ultrasonography detects nephrocalcinosis in cats with chronic kidney disease (CKD) by comparing it with micro-computed tomography and histopathology techniques.* -
  • Twelve kidneys from seven client-owned cats with CKD were examined, revealing that ultrasonography classified kidneys into three categories: absent, suspected, and present for nephrocalcinosis.* -
  • The results showed a strong correlation between macroscopic and microscopic assessments of nephrocalcinosis, suggesting that while ultrasonography may provide some insights, advanced imaging and histological methods are crucial for accurate detection.*
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Objectives: Distinguishing bacterial cystitis from subclinical bacteriuria is necessary for feline treatment protocols and antimicrobial stewardship. This can be challenging in cats with subcutaneous ureteral bypass (SUB) systems because they may present with lower urinary tract signs without bacteriuria. We investigated the relationship between positive urine culture and lower urinary tract signs in cats with SUBs, including factors associated with each.

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Background: Adolescent girls and young women in Uganda face numerous public health challenges including high HIV prevalence, teenage pregnancies, poor sexual and reproductive health rights, child marriage, and violence.

Objectives: This evidence review explores which interventions focusing on the empowerment of adolescent girls and young women to address these challenges are suitable for Ugandan policy.

Methods: We reviewed the literature to identify experimental studies and systematic reviews of interventions which improve sexual and reproductive health outcomes and/or prevent violence in adolescent girls and young women in low- and middle-income countries (LMICs).

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