Publications by authors named "R F Cowburn"

Liquid phase separation using aqueous biphasic systems (ABS) is widely used in industrial processes for the extraction, separation and purification of macromolecules. Using water as the single solvent, a wide variety of solutes have been used to induce phase separation including polymers, ionic liquids or salts. For each system, polymer-polymer, polymer-ionic liquid, polymer-salt or salt-salt, different driving forces were proposed to induce phase separation.

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Renal cell carcinoma (RCC) is the 7th commonest cancer in the UK and the most lethal urological malignancy; 50% of all RCC patients will die from the condition. However, if identified early enough, small RCCs are usually cured by surgery or percutaneous procedures, with 95% 10 year survival. This study describes a newly developed non-invasive urine-based assay for the early detection of RCC.

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Interfaces in heavy metal (HM) - antiferromagnetic insulator (AFI) heterostructures have recently become highly investigated and debated systems in the effort to create spintronic devices that function at terahertz frequencies. Such heterostructures have great technological potential because AFIs can generate sub-picosecond spin currents which the HMs can convert into charge signals. In this work we demonstrate an optically induced picosecond spin transfer at the interface between AFIs and Pt using time-domain THz emission spectroscopy.

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The design of complex, competing effects in magnetic systems-be it via the introduction of nonlinear interactions, or the patterning of three-dimensional geometries-is an emerging route to achieve new functionalities. In particular, through the design of three-dimensional geometries and curvature, intrastructure properties such as anisotropy and chirality, both geometry-induced and intrinsic, can be directly controlled, leading to a host of new physics and functionalities, such as three-dimensional chiral spin states, ultrafast chiral domain wall dynamics and spin textures with new spin topologies. Here, we advance beyond the control of intrastructure properties in three dimensions and tailor the magnetostatic coupling of neighbouring magnetic structures, an interstructure property that allows us to generate complex textures in the magnetic stray field.

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Objectives: To review urinary protein biomarkers as potential non-invasive, easily obtainable, early diagnostic tools in renal cell carcinoma (RCC).

Methods: A PubMed database search was performed up to the year 2020 to identify primary studies reporting potential urinary protein biomarkers for RCC. Separate searches were conducted to identify studies describing appropriate methods of developing cancer screening programmes and detection of cancer biomarkers.

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