Publications by authors named "R Ephraim"
Oxidative Stress and Cancer Risk in Schistosomiasis.
Oxid Med Cell Longev
December 2024
Schistosomiasis is considered one of the most devastating parasitic diseases globally, coming second only to malaria in terms of morbidity. The disease-causing parasite can inhabit the body for over a decade, leading to imbalances in the host's metabolic systems. The flukes and their eggs can illicit various immunological and metabolic complications resulting in the generation of reactive oxygen species (ROS).
View Article and Find Full Text PDFBackground And Aim: Chronic kidney disease (CKD) is becoming prevalent among people living with HIV/AIDS infection, with kidney dysfunction progressing to end-stage kidney disease (ESKD). We tested the diagnostic performance of creatinine, cystatin c, and the combined (creatinine + cystatin c)-based estimated glomerular filtration rate (eGFR) in assessing kidney dysfunction in HIV/AIDS patients on stable antiretroviral therapy (ART) at the Saltpond District Hospital, Ghana.
Methods: A cross-sectional study of 100 HIV/AIDS patients on ART at the Saltpond District Hospital was conducted.
Article Synopsis
- Vulvar carcinoma, primarily squamous cell carcinoma, is a rare form of cancer occurring in the external female genitalia, necessitating a multidisciplinary treatment approach often involving surgery and adjuvant therapy based on stage and other factors.
- A retrospective study conducted in India over eight years included 21 patients with vulvar cancer, analyzing disease stages, treatment methods, and outcomes, revealing a five-year survival rate of about 71%.
- The study highlighted the importance of individualized treatment plans and the need for strict protocols and regular follow-ups, especially in low-resource settings, to improve patient outcomes in this rare disease.
Introduction: Hepatitis C virus (HCV) infection is a silent epidemic that needs a comprehensive and contextualised approach to manage. Access to readily available, affordable and acceptable HCV point-of-care (POC) in vitro diagnostics (IVDs) is equally required to meet the global HCV goals. However, most guidelines for evaluating these IVDs such as the WHO prequalification process and country-specific standards disproportionately focus on diagnostic performance.
View Article and Find Full Text PDFAim And Objective: To evaluate the pretreatment cephalometric records on the dental, skeletal, soft tissue, and incisor relationship with a twin block functional appliance in class II malocclusion patients in and around Mahe; evaluate the posttreatment cephalometric records on the dental, skeletal, soft tissue, and incisor relationship with a twin block functional appliance in class II malocclusion patients in these children; and to compare cephalometrically certain dental, skeletal, and soft tissue points in pretreatment and posttreatment cephalograms in them.
Materials And Methods: This study was conducted on 20 class II patients in the mixed dentition period, who were treated with twin block therapy. Each had to meet the following criteria-(1) skeletal class II malocclusion with retrognathic mandible; (2) full cusp class II molar relationship; and (3) an angle of ANB of 50 or greater at the start of treatment.