Publications by authors named "R Elosua"
Background: Antidepressant drug treatment may be associated with weight gain, but long-term studies are lacking.
Methods: We included 3,127 adults (1,701 women) from the REGICOR study, aged 55.6 (SD = 11.
Interplay between lifestyle factors and polygenic risk for incident coronary heart disease in a large multiethnic cohort.
Int J Cardiol Cardiovasc Risk Prev
December 2024
Introduction: The objective of this study was to examine the interplay of polygenic risk and individual lifestyle factors (and a composite score of lifestyle) as antecedents of CHD in a large multiethnic cohort.
Methods: We used Genetic Epidemiology Resource in Adult Health and Aging (GERA) cohort participants free of CHD at baseline (n = 60,568; 67 % female; 18 % non-European). The individual and joint associations of smoking, Mediterranean diet pattern, level of physical activity and polygenic risk with incident CHD were assessed using Cox regression adjusting for genetic ancestry and non-mediating risk factors.
Context: Hip fractures are a major public health concern. Understanding their epidemiologic and biological links with diet and cardiovascular risk may have important implications for prevention.
Objective: To assess the dose-response association of Mediterranean diet (MD) adherence with the risk of hip fracture.
Background: Our aim was to determine the association between diet quality and depression incidence in the population-based REGICOR cohort study, Catalonia, Spain.
Methods: Prospective observational study using participants' baseline (2003-2006), follow-up (2007-2013) and clinical records data. Five diet quality scores were derived from a food frequency questionnaire (FFQ) at baseline: the relative Mediterranean Diet Score (rMED), the Modified Mediterranean Diet Score (ModMDS), a Dietary Approaches to Stop Hypertension (DASH) score, a Healthful Plant-based Diet Index (HPDI) and the World Health Organization Healthy Diet Indicator (WHO-HDI).
Article Synopsis
- The study evaluates the effectiveness of STEMI networks, focusing on out-of-hospital triage, in improving patient outcomes for ST elevation myocardial infarction (STEMI).
- It found that implementing these networks led to significant reductions in case-fatality (35%) and long-term mortality (27%), along with improvements in various patient conditions and treatment times.
- The positive effects were more pronounced in urban areas and high-income countries, emphasizing the importance of emergency transport systems in enhancing patient care.