Publications by authors named "R E Salmon"

The potential of artificial intelligence (AI) in digital pathology is limited by technical inconsistencies in the production of whole slide images (WSIs). This causes degraded AI performance and poses a challenge for widespread clinical application, as fine-tuning algorithms for each site is impractical. Changes in the imaging workflow can also compromise diagnostic accuracy and patient safety.

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Many of the implications of climate change for Aotearoa (New Zealand) remain unclear. To identify so-far unseen or understudied threats and opportunities related to climate change we applied a horizon-scanning process. First, we collated 171 threats and opportunities across our diverse fields of research.

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Article Synopsis
  • Alzheimer's disease (AD) is a complex condition marked by cognitive decline and neurodegeneration, with tau protein accumulation being a key feature and target for treatment.
  • Recent advancements in Artificial Intelligence (AI) have enhanced the drug discovery process, making it faster and more affordable.
  • In this study, researchers utilized a virtual screening tool to analyze 12 million compounds for tau aggregation inhibitors, ultimately identifying seven potential candidates after extensive filtering and molecular simulations.
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Introduction: Recurrent chromosome 16p13.11 microduplication has been characterised in the literature as a cause of developmental delay, learning difficulties and behavioural abnormalities. It is a neurosusceptibility locus and has incomplete penetrance and variable expression.

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