Molecular Identification and Bioinformatics Analysis of Moonlighting Proteins as Possible Antigenic Targets.

Background: Diseases of veterinary importance, such as bovine Anaplasmosis, cause significant economic losses. Due to this, the study of various proteins of the causal agent has focused on surface proteins. However, a vaccine for this disease is not yet available.

A Novel Receptor Binding Progesterone, a Possible Transregulation Mechanism in the -Host Interaction.

Background: Hormone receptors exert their function through binding with their ligands, which results in cellular signaling activation mediated by genomic or non-genomic mechanisms. The intrinsic molecular communication of tick and its host comprises an endocrine regulation involving hormones. In the present study, we performed a molecular and analysis of a Membrane Associated Progesterone Receptor in (RmMAPRC).

Draft genome sequencing of isolated from aborted Iraqi sheep.

Brucellosis remains a significant zoonotic disease, with maintaining endemicity in Middle Eastern nations. This study presents the draft genome sequencing of an Iraqi strain, representing a crucial step in monitoring virulence, antimicrobial resistance, and exploring the diversity and evolution of the genus.

An alternative vaccine target for bovine Anaplasmosis based on enolase, a moonlighting protein.

The discovery of new targets for preventing bovine anaplasmosis has moved away from focusing on proteins that have already been extensively studied in , including the Major Surface Proteins, Outer Membrane Proteins, and Type IV Secretion System proteins. An alternative is moonlighting or multifunctional proteins, capable of performing various biological functions within various cellular compartments. There are several reports on the role of moonlighting proteins as virulence factors in various microorganisms.

A Novel Estrogen Related Receptor (RmERR), a Molecular and In Silico Characterization of a Potential Protein Binding Estrogen.

The search for targets to control ticks and tick-borne diseases has been an ongoing problem, and so far, we still need efficient, non-chemical alternatives for this purpose. This search must consider new alternatives. For example genomics analysis is a widely applied tool in veterinary health studies to control pathogens.