Publications by authors named "R E Mbu"
Article Synopsis
- Hepatitis B virus (HBV) and hepatitis delta virus (HDV) co-infection is severe and can be transmitted from mother to child, with significant rates found in pregnant women in Cameroon.
- A study involving 1992 pregnant women revealed a 6.7% prevalence of HBsAg, with 32.3% of HBsAg-positive women also being anti-HDV antibody-positive and almost half showing detectable HDV RNA levels.
- Risk factors linked to HDV presence included multiple pregnancies and body modifications like tattoos, highlighting the need for awareness and preventive measures against maternal transmission of HDV.
Toward the elimination of hepatitis B: networking to promote the prevention of vertical transmission of hepatitis B virus through population-based interventions and multidisciplinary groups in Africa.
Front Public Health
April 2024
Article Synopsis
- In 2019, the WHO reported 81 million people with chronic hepatitis B in Africa, highlighting the need for prevention programs to stop mother-to-child transmission (MTCT) of HBV, which can lead to chronic infections.
- A network called the Mother-Infant Cohort Hepatitis B Network (MICHep B Network) was created in 2018, involving multiple African countries and the UK, aiming to promote effective initiatives for preventing MTCT of HBV.
- The network has conducted various studies and workshops to raise awareness and build capacity around HBV, revealing a significant acceptability of the hepatitis B vaccine among families in Cameroon and Zimbabwe.
Stillbirth rate and associated factors at the Bamenda Regional hospital, North-West region, Cameroon, from 2018 to 2022: a case control study.
BMC Pregnancy Childbirth
April 2024
Background: Stillbirth is a common adverse pregnancy outcome worldwide, with an estimated 2.6 million stillbirths yearly. In Cameroon, the reported rate in 2015 was 19.
View Article and Find Full Text PDFPrevention of mother-to-child transmission of hepatitis B virus (HBV) infection is a cornerstone of efforts to support progress towards elimination of viral hepatitis. Current guidelines recommend maternal screening, antiviral therapy during the third trimester of high-risk pregnancies, universal and timely HBV birth dose vaccination, and post-exposure prophylaxis with hepatitis B immunoglobulin for selected neonates. However, serological and molecular diagnostic testing, treatment and HBV vaccination are not consistently deployed, particularly in many high endemicity settings, and models predict that global targets for reduction in paediatric incidence will not be met by 2030.
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