Actomyosin contraction in the follicular epithelium provides the major mechanical force for follicle rupture during ovulation.

Ovulation is critical for sexual reproduction and consists of the process of liberating fertilizable oocytes from their somatic follicle capsules, also known as follicle rupture. The mechanical force for oocyte expulsion is largely unknown in many species. Our previous work demonstrated that ovulation, as in mammals, requires the proteolytic degradation of the posterior follicle wall and follicle rupture to release the mature oocyte from a layer of somatic follicle cells.

Medical Students' Preferences on Practicing Intravenous Insertion on Each Other and Via Simulation.

Medical students have traditionally practiced painful procedures such as intravenous (IV) line insertion on each other. Recently, there has been more emphasis on learning through simulation. Our study investigated students' attitudes regarding IV line insertion training, focusing on their anxiety, expectation to learn empathy, learning preference, and litigiousness.

Prevalence rates of neurodegenerative diseases versus human exposures to heavy metals across the United States.

Novel means are needed to identify individuals and subpopulations susceptible to and afflicted by neurodegenerative diseases (NDDs). This study aimed to utilize geographic distribution of heavy metal sources and sinks to investigate a potential human health risk of developing NDDs. Known or hypothesized environmental factors driving disease prevalence of Alzheimer's Disease (AD), Parkinson's Disease (PD), and amyotrophic lateral sclerosis (ALS) are heavy metals, including arsenic (As), cadmium (Cd), manganese (Mn) and mercury (Hg).

PAPγ associates with PAXT nuclear exosome to control the abundance of PROMPT ncRNAs.

Pervasive transcription of the human genome generates an abundance of RNAs that must be processed and degraded. The nuclear RNA exosome is the main RNA degradation machinery in the nucleus. However, nuclear exosome must be recruited to its substrates by targeting complexes, such as NEXT or PAXT.

Home language variation in the narratives of urban First Nations Australian children in their first year of school.

First Nations children may speak a dialect of English that has different grammatical rules from Standard Australian English (school language). Limited studies have investigated Aboriginal English (home language) dialect in First Nations children and its impact on differential diagnosis of language disorder. This study measured the density of home language dialect and grammatical accuracy in oral narratives produced by typically developing First Nations children.