Publications by authors named "R E Collis"
Antimicrobial resistance is a global public and animal health concern. Antimicrobial resistance genes (ARGs) have been detected in dairy farm environments globally; however, few longitudinal studies have utilized shotgun metagenomics for ARG surveillance in pasture-based systems. This 15-month study aimed to undertake a baseline survey using shotgun metagenomics to assess the relative abundance and diversity of ARGs in two pasture-based dairy farm environments in New Zealand with different management practices.
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- The Obstetric Bleeding Study UK (OBS UK) is a randomized controlled trial aimed at addressing postpartum hemorrhage, initially developed in Wales, which has noted improved maternal outcomes but faces limitations in generalizability due to demographic homogeneity in the Welsh sample.* -
- To enhance the diversity and inclusivity of the trial, maternity units across the UK were selected based on their representation of various ethnic and socioeconomic profiles, with a focus on ensuring results are applicable to a broader population.* -
- An interactive dashboard was created using census data to visualize and compare the demographics of each participating maternity unit, confirming that the trial sites reflect the wider UK's ethnic and socioeconomic diversity, despite some inconsistencies in data availability across different locations.*
Article Synopsis
- This study analyzes the proteomic differences within specific regions of the bovine heart, aiming to understand variations beyond just whole cardiac chambers.
- Researchers identified three distinct proteomes based on samples taken from different heart sections, revealing relationships between proteomic variations and cardiac regions like the outer walls of ventricles and the septum.
- Findings showed differences in protein abundances related to energy metabolism, and a specific disease-related protein was linked predominantly to the outer wall of the left ventricle, emphasizing that proteomic diversity doesn't always align with anatomical structures.
Freshwater samples (n = 199) were obtained from 41 sites with contrasting land-uses (avian, low impact, dairy, urban, sheep and beef, and mixed sheep, beef and dairy) and the E. coli phylotype of 3980 isolates (20 per water sample enrichment) was determined. Eight phylotypes were identified with B1 (48.
View Article and Find Full Text PDFBackground: Viscoelastometric haemostatic assays (VHA) give rapid information on coagulation status, allowing individualised resuscitation.
Methods: This paper compares outcomes from two observational studies of postpartum haemorrhage (PPH) in the same institution, before and after practice changed from fixed ratio empirical transfusion of coagulation products with laboratory coagulation testing to VHA-guided fibrinogen replacement incorporated into an enhanced PPH care bundle. In both studies, all blood samples were taken near 1000 mL qualitative blood loss (QBL).