Publications by authors named "R E Chinnock"
The IPTA Nashville consensus conference on post-transplant lymphoproliferative disorders after solid organ transplantation in children: IV-consensus guidelines for the management of post-transplant lymphoproliferative disorders in children and adolescents.
Pediatr Transplant
August 2024
Article Synopsis
- * Strong recommendations include reducing immunosuppression as an initial management step and using the anti-CD20 monoclonal antibody (rituximab), as well as chemotherapy in specific cases.
- * There is a lack of large randomized phase III trials for treating PTLD in pediatrics, leading to reliance on clinical experience, and the report emphasizes the need for future research on this topic.
Correction: Ending the HIV Epidemic in Black America: Qualitative Insights Following COVID-19.
J Racial Ethn Health Disparities
March 2024
Ending the HIV Epidemic in Black America: Qualitative Insights Following COVID-19.
J Racial Ethn Health Disparities
February 2024
Background: The disproportionate effects of the human immunodeficiency virus (HIV) and the Coronavirus 2019 (COVID-19) on Black American communities highlight structural systems rooted in racism and must be addressed with national strategies that improve both biomedicine and social determinants of health.
Purpose: The purpose of this study was to qualitatively examine the experiences and interpretations of experts in the HIV workforce (local, state, and national HIV-related organizations) regarding the state of HIV and COVID-19 among Black Americans.
Methods: Within key informant interviews and a focus group recorded and transcribed verbatim, fifteen members of the HIV workforce and Black community described their experiences and provided insights to inform ending the negative outcomes resulting from HIV and COVID-19.
Article Synopsis
- Heart transplantation for infants with hypoplastic left heart syndrome has seen significant success since the 1980s, with about 90% of children reaching their first year post-transplant thanks to advancements in clinical practices and research.
- Despite these improvements, challenges remain in ensuring long-term survival into adulthood, particularly due to high wait-list mortality and issues like cardiac allograft vasculopathy, which can lead to transplant failure.
- There is a need for targeted funding and research that addresses the unique risks faced by pediatric transplant recipients, as current funding heavily favors adult patients, limiting progress in pediatric care.
The IPTA Nashville Consensus Conference on Post-Transplant lymphoproliferative disorders after solid organ transplantation in children: III - Consensus guidelines for Epstein-Barr virus load and other biomarker monitoring.
Pediatr Transplant
February 2024
Article Synopsis
- The International Pediatric Transplant Association held a conference to create guidelines for managing post-transplant lymphoproliferative disorders (PTLD) in children, focusing on how to use biomarkers like Epstein-Barr virus (EBV) levels for patient care.
- The group recommends using "EBV DNAemia" for measuring EBV DNA in blood and advises caution when comparing results from different labs. They concluded both whole blood and plasma can be used for testing, depending on the clinical situation.
- It is suggested that quantitative EBV DNAemia testing can help identify children at risk for PTLD, especially those who were EBV negative before their transplant, but overall routine surveillance is not recommended for