Publications by authors named "R E Cervera"
: The clinical and laboratory features of patients with non-criteria obstetric antiphospholipid syndrome (NC-OAPS), as well as their pregnancy outcomes and ideal treatment are not clearly determined. The aim of this study is to describe the characteristics and outcomes of pregnancies in NC-OAPS and compare them with an obstetric APS (OAPS) cohort. : This is a retrospective study conducted on a cohort of women referred to a high-risk obstetric unit of a tertiary hospital.
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- - A treat-to-target (T2T) approach focuses on setting specific therapeutic goals for disease management, requiring regular check-ins and treatment adjustments to improve patient outcomes.
- - Implementing T2T in Antiphospholipid Syndrome (APS) is challenging due to the disease's diverse symptoms and the absence of reliable markers to measure disease activity.
- - Despite these difficulties, T2T strategies remain crucial for APS management, aiming to control the disease better, minimize recurrence risks, and improve patients' overall quality of life.
Article Synopsis
- - This study examined the occurrence and effects of antinuclear antibodies (ANA) in patients with antiphospholipid antibodies (aPL) but without other systemic autoimmune diseases, using data from the APS ACTION Registry.
- - Among the 430 analyzed patients, 56% tested positive for ANA, revealing significant links between ANA positivity and various autoimmune features like hematologic issues and joint involvement.
- - Despite the presence of these autoimmune characteristics in ANA-positive patients, the study found no connection between ANA status and complications related to thrombosis or pregnancy; interestingly, ANA-negative patients had more pregnancies and live births.