Unilateral Blastomyces dermatitidis optic neuropathy case report and systematic literature review.

Objective: To describe the clinical and histopathologic findings of a unique case of isolated optic nerve Blastomyces dermatitidis infection and to summarize the ophthalmic blastomycosis literature.

Design: Case report and systematic literature review.

Methods: A 70-year-old healthy man experienced impaired vision in his left eye.

Wegener granulomatosis presenting as bilateral loss of vision.

We describe a man presenting with bilateral loss of vision secondary to a branch retinal artery occlusion and ischemic optic neuropathy, in turn related to underlying Wegener granulomatosis (WG). This case is unusual, because the simultaneous development of branch retinal artery occlusion and anterior ischemic optic neuropathy has, to our knowledge, not been reported in WG. Furthermore, only rarely does WG cause bilateral vision loss.