Artificial intelligence, recessionary pressures and population health.

Economic and labour policies have a considerable influence on health and well-being through direct financial impacts, and by shaping social and physical environments. Strong economies are important for public health investment and employment, yet the rapid rise of generative artificial intelligence (AI) has the potential to reshape economies, presenting challenges beyond mere temporary market disruption. Generative AI can perform non-routine cognitive tasks, previously unattainable though traditional automation, creating new efficiencies.

Mental Well-being in Menopause.

The hormonal changes that accompany the transition to menopause are disruptive to most women, and for some, mental health maybe adversely affected. Depressive symptoms and major depression are the best-studied conditions in association with menopause, but anxiety, executive function, and comorbid pre-existing psychiatric conditions all influence the symptomatology that women will experience during this phase of their lives. The epidemiology, diagnosis, and evidence-based treatment guidelines for perimenopausal patients are discussed.

Synthesis and Polymerization of Thiophene-Bearing 2-Oxazolines and 2-Oxazines.

Intrinsically conductive polymers have garnered a great deal of attention for use in medical and bioelectronic applications. Despite this, challenges associated with the mechanical stability, processability, and fabrication of conducting polymers have limited their utility. To circumvent these limitations, thiophene substituted 2-oxazolines (2Ox) and 2-oxazines (2Ozi) are introduced, which can be polymerized to form a thermally stable and potentially melt-processable polymers as precursors for conductive polymers.

2024 White Paper on Recent Issues in Bioanalysis: Three Way-Cross Validation; Urine Clinical Analysis; Automated Methods; Regulatory Queries on Plasma Protein Binding; Automated Biospecimen Management; ELN Migration; Ultra-Sensitivity Mass Spectrometry ( - Recommendations on Advanced Strategies for Mass Spectrometry Assays, Chromatography, Sample Preparation and BMV/Regulated Bioanalysis - Regulatory Agencies' Inputs on Regulated Bioanalysis/BMV).

The 18 Workshop on Recent Issues in Bioanalysis (18 WRIB) took place in San Antonio, TX, USA on May 6-10, 2024. Over 1100 professionals representing pharma/biotech companies, CROs, and multiple regulatory agencies convened to actively discuss the most current topics of interest in bioanalysis. The 18 WRIB included 3 Main Workshops and 7 Specialized Workshops that together spanned 1 week to allow an exhaustive and thorough coverage of all major issues in bioanalysis of biomarkers, immunogenicity, gene therapy, cell therapy and vaccines.