Invited review: Udder cleft dermatitis in dairy cows.

Udder cleft dermatitis (UCD) is a common dermatological condition of the udder skin in dairy cows. It is generally considered to be a multifactorial disease, being described in a rather limited amount of literature. Its cow and within-herd prevalence widely ranges between studies depending on the study characteristics, environment and breed.

Multi-omics analysis elucidates the host-microbiome interplay in severe udder cleft dermatitis lesions in dairy cows.

Udder cleft dermatitis is a skin disease in dairy cattle that is characterized by painful, large open wounds between the udder halves or at the front udder attachment. Its impact on animal welfare and production warrants an in-depth investigation of its pathogenesis. The present study delves into the pathophysiology of severe udder cleft dermatitis, employing a multi-omics approach by integrating transcriptomic and metagenomic data obtained from samples of severe udder cleft dermatitis lesions and healthy udder skin of dairy cattle.

Clostridium perfringens chitinases, key enzymes during early stages of necrotic enteritis in broiler chickens.

The interaction between bacteria and the intestinal mucus is crucial during the early pathogenesis of many enteric diseases in mammals. A critical step in this process employed by both commensal and pathogenic bacteria focuses on the breakdown of the protective layer presented by the intestinal mucus by mucolytic enzymes. C.

Oral vaccination of young broilers with a live Typhimurium vaccine reduces caecal and internal organ colonization following a Infantis challenge in a seeder-bird model.

Poultry products are an important source of foodborne infections in humans. Amongst these, the prevalence of Infantis is rising. In this study, the protection efficacy of an authorized live-attenuated Typhimurium vaccine against Infantis, was examined using a seeder-bird model in broilers.

An in-depth investigation of the microbiota and its virulence factors associated with severe udder cleft dermatitis lesions.

Udder cleft dermatitis (UCD) is a skin condition affecting the anterior parts of the udder in dairy cattle. In the present study, we aimed to shed light on the microbiota in severe UCD lesions versus healthy udder skin by putting forward a taxonomic and functional profile based on a virulence factor analysis. Through shotgun metagenomic sequencing, we found a high proportion of bacteria in addition to a low abundance of archaea.