Publications by authors named "R Dornier"
Article Synopsis
- This study explores how adaptive optics-transscleral flood illumination (AO-TFI) imaging can provide detailed insights into retinal pigment epithelium (RPE) changes in cases of central serous chorioretinopathy (CSCR) compared to standard clinical imaging.
- Researchers analyzed 125 AO-TFI images from both affected and healthy eyes, finding significant changes in RPE contrast and patterns during different stages of CSCR.
- The findings indicate that AO-TFI not only gives a clearer picture of outer retinal abnormalities but also reveals previously undetectable RPE issues, underscoring the need for further research to assess the clinical implications of these findings in understanding CSCR progression.
Objective: To image healthy retinal pigment epithelial (RPE) cells in vivo using Transscleral OPtical Imaging (TOPI) and to analyze statistics of RPE cell features as a function of age, axial length (AL), and eccentricity.
Design: Single-center, exploratory, prospective, and descriptive clinical study.
Participants: Forty-nine eyes (AL: 24.
Shifted Excitation Raman Difference Spectroscopy (SERDS) is a non-destructive chemical analysis method capable of removing the fluorescence background and other disturbances from the Raman spectrum, thanks to the independence of the fluorescence with respect to the small difference in excitation wavelength. The spectrum difference is computed in a post-processing step. Here, we demonstrate the use of a lock-in camera to obtain an on-line analog SERDS spectra allowing longer exposure times and no saturation, leading to an improved Signal-to-Noise Ratio (SNR) and reduced data storage.
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