Publications by authors named "R Dodd"
A consistent feature of lung injury is a rapid and sustained accumulation of hyaluronan (HA). The rodent gut-dwelling nematode (Nb) induces tissue damage as it migrates through the lungs. Type 2 immune responses are essential for the repair of the lungs, hence Nb infection is a well-established model to study immune-mediated lung repair.
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- Hyaluronan (HA) is a key component of lung extracellular matrix that increases after influenza or SARS-CoV-2 infections.
- A study by Hellman et al. found that fragmented HA builds up in the lungs of COVID-19 patients, correlating with decreased lung function several months post-infection.
- The research highlights HA's potential as a biomarker for COVID-19 severity but also emphasizes the need for further investigation into HA’s role and its interactions within the lung's immune response.
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by renal phosphate wasting and impaired bone mineralization secondary to secretion of fibroblast growth factor 23 (FGF23) from mesenchymal tumors (phosphaturic mesenchymal tumors, PMTs). PMTs have wide anatomical distribution but typically affect extremities and craniofacial bones. Diagnosis of TIO/PMT is often delayed, and a high index of suspicion is essential in patients with unexplained fractures, but many physicians lack familiarity with TIO/PMT and simply attribute fractures to the more common diagnosis of osteoporosis.
View Article and Find Full Text PDFObjective: Patient reported experience measures (PREMs) are common tools utilised in hospitals to support quality improvements, allow consumers to provide feedback on care experiences and can be used to support consumers' hospital selections. This study aimed to understand the views and opinions of private hospital staff on PREM use and the utility of PREMs as a consumer decision-making tool.
Method: Qualitative, semi-structured interview study conducted via telephone between March-June 2023.
Background: Transfusion-transmissible infection (TTI) prevalence among US blood donors has been widely documented. Here we estimate the prevalence of donors presenting with ≥2 TTIs (multiple infections past or present referred to as coinfections) and describe their demographics and associations.
Methods: Data from the Transfusion-Transmissible Infections Monitoring System were compiled for October 2020-September 2023 (3 years).