The diagnostic accuracy of point-of-care nucleic acid-based isothermal amplification assays for scrub typhus: a systematic review and meta-analysis.

Introduction: The diagnosis and detection of pathogens such as and is a cause of major concern among the public health community. Unavailability of rapid, cost-effective diagnostic assays contributes to delayed diagnosis and timely treatment. Using the methodology of systematic reviewing and meta-analysis, the study aimed to synthesize and compare the diagnostic performances of all the available isothermal assays for the detection of classical rickettsial diseases.

Mutation Spectrum Analysis of BRCA1/2 Genes for Hereditary Breast and Ovarian Cancer in the Indian Population.

Objective: The objective of this study was to determine the prevalence and spectrum of genetic mutations linked to inherited breast and ovary cancer (HBOC) in the Indian population, and to evaluate the correlation of BRCA mutation types, frequency, and incidence with age, gender, and personal and family history.

Methods: A retrospective cohort of 500 Indian HBOC patients, meeting NCCN criteria who underwent BRCA1/2 testing from 2017 to 2023 were shortlisted for this study. The anonymized data was retrieved from medical records.

Evaluating Emotional Intelligence in Medical Students: A Comparative Analysis of Their Trait Emotional Intelligence (TEI) Scores Before and During the COVID-19 Pandemic.

Medical education, which generally relied heavily on intelligence quotients, has found a new value in emotional intelligence (EI), specifically after the challenges faced during the COVID-19 pandemic. The COVID-19 pandemic has had some apparent and some intangible effects, as this required an emergency switch to online teaching and learning.  Aim: This study was conducted to compare the trait emotional intelligence (TEI) score of medical undergraduates with the increasing number of years of medical curriculum.

Outcomes following laparoscopic adrenalectomy: Experience of more than two decades at a tertiary care centre.

Introduction: Laparoscopic transperitoneal adrenalectomy was first described by Gagner M et al . Here, we present our experience of more than two decades of laparoscopic adrenalectomy performed in a single surgical unit at a tertiary care centre.

Patients And Methods: A prospectively collected database of patients undergoing laparoscopic adrenalectomy from December 1994 to May 2020 was analysed retrospectively.

One-Step Multiplex Polymerase Chain Reaction Assay for the Detection of Major Disease-Transmitting Mosquito Vectors in India.

Mosquitoes are important vectors that transmit viral, protozoan, and helminthic diseases across the world. Climate change and unplanned urbanization are accelerating the spread of these diseases. Controlling vector-borne diseases can be performed most effectively through vector control.