Publications by authors named "R Dimmitt"
Introduction: We previously reported that endoscopic repair of a Type 1 Laryngeal Cleft (LC1) or Deep Interarytenoid Groove (DIG) improves swallowing function postoperatively. However, caregivers often ask about the timeline to resolution of the need for thickening. This study re-examines this cohort to answer this important caregiver-centered question.
View Article and Find Full Text PDFFactors Affecting the Gut Microbiome in Pediatric Intestinal Failure.
J Pediatr Gastroenterol Nutr
September 2023
Background: There is little data on gut microbiome and various factors that lead to dysbiosis in pediatric intestinal failure (PIF). This study aimed to characterize gut microbiome in PIF and determine factors that may affect microbial composition in these patients.
Methods: This is a single-center, prospective cohort study of children with PIF followed at our intestinal rehabilitation program.
Article Synopsis
- The study aimed to find which surgical treatment for premature infants with necrotizing enterocolitis (NEC) or isolated intestinal perforation (IP) led to lower rates of death or neurodevelopmental impairment (NDI).
- Researchers conducted a large trial with 310 infants across 20 US centers, comparing laparotomy and peritoneal drainage as initial treatments and assessing outcomes at 18 to 22 months.
- Results showed similar rates of death or NDI overall (69% for laparotomy vs. 70% for drainage), but preoperative diagnosis influenced outcomes, with laparotomy being more beneficial for NEC but less for IP.
Optimal timing and technique for endoscopic management of dysphagia in pediatric aerodigestive patients.
Int J Pediatr Otorhinolaryngol
November 2021
Introduction: The best strategy to manage an interarytenoid defect [Type 1 laryngeal cleft (LC-1) or deep interarytenoid groove (DIG)] in pediatric aerodigestive patients with dysphagia remains uncertain. This study compared benefit of interarytenoid augmentation (IAA) to suture repair or clinical observation alone in pediatric patients.
Methods: A 3-year retrospective, single-center analysis of children with dysphagia undergoing endoscopic airway evaluation was performed.
Background: In this study, we aim to determine the effect of scheduled antibiotics on gut microbiome in pediatric intestinal failure (IF) and to evaluate the effect of the gut microbiome on nutrition outcomes in IF.
Methods: Fecal samples were collected at regular intervals from pediatric patients with IF for gut microbiome comparison between 2 cohorts: (group 1) those on scheduled prophylactic antibiotics and (group 2) those who were not on scheduled antibiotics. Gut microbiome composition and diversity were compared among the 2 cohorts.