Publications by authors named "R Deulofeu"
Nutrition is fundamental for brain development, but relatively little is known about water-soluble vitamin (WSV) levels and the effect of supplementation on psychiatry symptoms in children and adolescents (CAD) with psychiatric disorders. Our team systematically reviewed all studies concerning WSV abnormalities or supplementation in CAD with any psychiatric disorder. We searched for original studies published between 1990 and 15/05/2020 which were not based on retrospective chart review and which included WSV blood level measurements or investigated the effect of WSV supplementation on psychiatric symptoms in psychiatric patients aged 18 or under.
View Article and Find Full Text PDFIn the course of pregnancy, increasing importance is being placed on maintaining optimal fatty acid (FA) levels and particularly n-3 PUFAs to ensure correct fetal development. However, reference ranges for FA have been reported in only a few studies. Our objective is to provide quantitative reference intervals for SFAs, MUFAs, and PUFAs (n-6 and n-3) in a large population of healthy pregnant women from a developed country.
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- Acute intermittent porphyria (AIP) is a rare metabolic disorder caused by specific gene mutations, leading to elevated total homocysteine (tHcy) levels in many patients.
- In a study with 37 AIP patients, 68% exhibited hyperhomocysteinemia (HHcy), particularly those with recurrent symptoms on heme arginate treatment, showing significant variations in tHcy levels over time.
- The study found that along with high tHcy, patients had low levels of key nutrients like pyridoxal-5'-phosphate and folate, and notable increases in other amino acids after starting givosiran treatment, suggesting a complex link between AIP treatment and metabolic changes.
Objective: To compare changes in microcirculation blood flow (MCBF) between pulsatile and continuous flow insufflation. Transanal total mesorectal excision (TaTME) was developed to improve the quality of the resection in rectal cancer surgery. The AirSeal IFS® insufflator facilitates the pelvic dissection, although evidence on the effects that continuous flow insufflation has on MCBF is scarce.
View Article and Find Full Text PDFBackground: To assess whether serum osteoprotegerin (OPG) and/or fetuin-A predict mortality and cardiovascular (CV) morbidity and mortality in hemodialysis patients.
Methods: Multicenter, observational, prospective study that included 220 hemodialysis patients followed up for up to 6 years. Serum OPG and fetuin-A levels were measured at baseline and their possible association with clinical characteristics, CV risk biomarkers, carotid ultrasonographic findings, as well as their association with overall and CV mortality and CV events were assessed.