Publications by authors named "R Desailloud"
At present, primary hyperparathyroidism is most often discovered in an asymptomatic patient, but can sometimes be revealed by a renal or bone complications. In all cases, a full work-up is recommended, with assessment of renal function (glomerular filtration rate), 24-hour calciuria, screening for risk factors for lithiasis, and renal and urinary tract imaging (ultrasound or CT scan) to look for stones or nephrocalcinosis. Bone densitometry, with measurements of the spine, femur and radius, is the recommended reference test for demineralization.
View Article and Find Full Text PDFPurpose: To assess the incidence of congenital hypothyroidism (CH) and acquired hypothyroidism (AH) between 2014 and 2019 in continental France.
Methods: New cases of CH and AH were identified using the French National Health Data System (Système Nationale des Données de Santé, SNDS). Temporal trends were studied using linear regression models.
Article Synopsis
- * The French Endocrine Society and associated organizations created a reference document to address the complexities of managing these tumors, which can recur and lead to serious health issues, including impaired quality of life for patients, especially those with hypothalamic syndrome.
- * Recent research has identified two tumor types—papillary and adamantinomatous—with different molecular signatures and treatment strategies, prompting ongoing developments in therapeutic options, including new medications for associated symptoms like hyperphagia.
Article Synopsis
- - Pheochromocytoma and paraganglioma (PPGL) are rare tumors with a significant genetic component, leading to the need for genetic screening for specific variants.
- - Over 21 years (2001-2022), an endocrine oncogenetic lab studied 606 PPGL cases, using both traditional Sanger sequencing and modern next-generation sequencing (NGS) to identify genetic variants in patients and their relatives.
- - The study found that 27.2% of index cases had pathogenic variants, with variability in symptoms and tumor characteristics among different families, emphasizing the importance of genetic screening for tailored patient management.
Background: Epidemiological data regarding thyroid diseases are lacking, in particular for occupationally exposed populations.
Objectives: To compare the risk of hypothyroidism and hyperthyroidism between farming activities within the complete population of French farm managers (FMs).
Methods: Digital health data from retrospective administrative databases, including insurance claims and electronic health/medical records, was employed.