Publications by authors named "R Dell'Oro"
Article Synopsis
- The study investigates the link between resting heart rates above 70 beats/minute in type 2 diabetes mellitus (T2D) patients and increased cardiovascular risk, aiming to determine if this reflects heightened sympathetic nervous system activity.
- Results indicate that higher heart rates were associated with greater muscle sympathetic nerve activity (MSNA) and norepinephrine levels, suggesting a significant relationship between heart rate and sympathetic overdrive in T2D patients.
- The findings highlight the importance of monitoring heart rates in T2D, as they may help identify patients with increased sympathetic activity, warranting further research into lifestyle and medication strategies that could potentially mitigate this risk.
Article Synopsis
- - This study analyzed the link between metabolically healthy overweight/obese adults and major cardiovascular events (MACE) using data from 15,904 participants over 11.8 years, focusing on how LDL-cholesterol levels affect this relationship.
- - Among participants younger than 70, being overweight/obese raised the risk of MACE significantly, while older adults had a lower risk despite having high BMI.
- - Including LDL-cholesterol in the definition of healthy metabolism showed that metabolically healthy overweight/obese individuals have no increased risk of MACE compared to normal weight individuals, challenging standard assessments of health risk.
Article Synopsis
- The study examined the relationship between Cardio-Ankle Vascular Index (CAVI) and nocturnal blood pressure (BP) fall in 491 participants from the PAMELA study after 10 and 25 years.
- It found that while both CAVI and left ventricular mass index (LVMI) were correlated with nocturnal SBP fall, only LVMI remained significant after adjusting for age and sex.
- The results suggest that CAVI is not linked to the degree of nighttime BP drop, but it can help identify nocturnal hypertension and improve cardiovascular risk assessment in the general population.