Adaptations Associated With an After-School Strength and Conditioning Program in Middle-School-Aged Boys: A Quasi-Experimental Design.

High-intensity strength and conditioning programs aimed at improving youth performance are becoming increasingly prevalent. The purpose of this study was to investigate the effects of a 16-week after-school strength and conditioning program on performance and body composition in middle-school-aged boys. Subjects in the training group (n = 16, mean age = 11.

The time course of short-term hypertrophy in the absence of eccentric muscle damage.

Background: It has been proposed that the increase in skeletal muscle mass observed during the initial weeks of initiating a resistance training program is concomitant with eccentric muscle damage and edema.

Purpose: We examined the time course of muscle hypertrophy during 4 weeks of concentric-only resistance training.

Methods: Thirteen untrained men performed unilateral concentric-only dumbbell curls and shoulder presses twice per week for 4 weeks.

Does reactivating a witnessed memory increase its susceptibility to impairment by subsequent misinformation?

In a recent article, Chan and LaPaglia (2013) provided arguments and evidence to support the claim that reactivating a witnessed memory (by taking a test) renders the memory labile and susceptible to impairment by subsequent misinformation. In the current article, we argue that Chan and LaPaglia’s (2013) findings are open to alternative interpretations, and further test the hypothesis that reactivation increases a witnessed memory’s susceptibility to impairment. To this end, the current studies used a different set of materials and a different measure of memory impairment, the Modified Recognition Test (McCloskey & Zaragoza, 1985).

gp120 modulates the biology of human hepatic stellate cells: a link between HIV infection and liver fibrogenesis.

Objective: In patients with hepatitis C virus (HCV)/HIV co-infection, a faster progression of liver fibrosis to cirrhosis has been reported. In this study, an investigation was carried out to determine whether gp120, an HIV envelope protein, modulates the biology of human hepatic stellate cells (HSCs), key cell types in the pathogenesis of fibrosis.

Methods: Myofibroblastic HSCs were isolated from normal human liver tissue.

Long-term outcomes of office-based buprenorphine/naloxone maintenance therapy.

Background: Buprenorphine/naloxone was approved by the FDA for office-based opioid maintenance therapy (OMT), with little long-term follow-up data from actual office-based practice. 18-Month outcome data on the office-based use of buprenorphine/naloxone (bup/nx) and the impact of socioeconomic status and other patient characteristics on the duration and clinical effects of bup/nx are reported.

Methods: This retrospective chart review and cross-sectional telephone interview provide treatment retention of opioid-dependent patients receiving bup/nx-OMT in an office-based setting.