Publications by authors named "R D Velayuthan"
Article Synopsis
- The rise of invasive fungal infections (IFIs) is notably higher in patients with hematological malignancies due to their weakened immune systems.
- Key risk factors for developing IFIs include older age, use of immunosuppressive drugs, low white blood cell counts (neutropenia), and the presence of catheters.
- The study highlights a lack of epidemiological data on IFIs in Asian patients and explores diagnostic and management challenges over the past decade (2011-2021).
Background: Single chamber atrial pacemaker should be sufficient for patients with sinus node dysfunction (SND) with normal atrioventricular (AV) conduction. However, most patients undergo dual chamber pacemaker implantation because of concern of new onset AV block. The annual incidence of new AV block has been reported from 0.
View Article and Find Full Text PDFWe report the isolation of a rare Gram-positive coccobacillary bacterium from synovial fluids of a patient with periprosthetic joint infection on three occasions over an 8-month period. As routine microbiological methods were not able to identify the isolate definitely, sequence analyses of the bacterial 16S ribosomal RNA gene and whole genome were performed. Analysis of the bacterial 16S ribosomal RNA gene showed the highest similarity (98.
View Article and Find Full Text PDFBackground: In recent years, the increase in antibiotics usage locally has led to a worrying emergence of multi-drug resistant organisms (MDRO), with the Malaysian prevalence rate of methicillin-resistant Staphylococcus aureus (MRSA) ranging from 17.2 to 28.1% between 1999 and 2017.
View Article and Find Full Text PDFArticle Synopsis
- Neoscytalidium dimidiatum and Bipolaris species are plant-pathogenic fungi that can also cause human diseases, as found in recent patient samples.
- The genome of N. dimidiatum was sequenced and compared to B. papendorfii, revealing important genetic similarities related to their ability to infect a wide range of hosts.
- The study highlights key genes involved in melanin production, nutrient uptake, and the breakdown of plant materials, as well as factors contributing to their pathogenicity in skin and nail infections, which sets the stage for future research on their survival and infection mechanisms.