Normothermic machine perfusion of explanted livers: Exploratory study of an alternative translational model for end-stage liver disease.

Background: Normothermic machine perfusion (NMP) is a technique for donor liver preservation and assessment in transplantation. NMP has gained momentum recently by enabling safer use of higher risk organs via organ viability assessment. It also offers a platform for investigating ex vivo organ biology.

Capturing spontaneous interactivity: a multi-measure approach to analyzing the dynamics of interpersonal coordination in dance improvisation.

Introduction: Interpersonal coordination is widely acknowledged as critical to relating with, connecting to, and understanding others, but the underlying mechanisms of this phenomenon are poorly understood. Dance-particularly improvised dance-offers a valuable paradigm for investigating the dynamics of interpersonal coordination due to its inherent ability to connect us. However, conventional approaches to studying coordination often fail to capture the co-creative spontaneity that is intrinsic to such interactions.

Development and validation of an LC‒MS/MS method for the determination of cyclocreatine phosphate and its related endogenous biomolecules in rat heart tissues.

The cardioprotective drug cyclocreatine phosphate has been awarded Food and Drug Administration-orphan drug designation for the prevention of ischemic injury to enhance cardiac graft recovery and survival in heart transplantation. Cyclocreatine phosphate is the water-soluble derivative of cyclocreatine. Estimating the levels of Cyclocreatine phosphate, Adenosine triphosphate, Creatine Phosphate, Creatine and Cyclocreatine helps us in understanding the energy state as well as evaluating the heart cells' function.

isolates contain frequent heterozygous structural variants and transposable elements within genes and centromeres.

The human fungal pathogen poses a significant burden on global health, causing high rates of mortality and antifungal drug resistance. is a heterozygous diploid organism that reproduces asexually. Structural variants (SVs) are an important source of genomic rearrangement, particularly in species that lack sexual recombination.

Racial disparities in prostate cancer in the UK and the USA: similarities, differences and steps forwards.

In the USA, Black men are approximately twice as likely to be diagnosed with and to die of prostate cancer than white men. In the UK, despite Black men having vastly different ancestral contexts and health-care systems from Black men in the USA, the lifetime risk of being diagnosed with prostate cancer is two-to-three times higher among Black British men than among white British men and Black British men are twice as likely to die of prostate cancer as white British men. Examination of racial disparities in prostate cancer in the USA and UK highlights systemic, socio-economic and sociocultural factors that might contribute to these differences.