Publications by authors named "R D Thiagarajan"

Patients with restrictive cardiomyopathy (RCM) and hypertrophic cardiomyopathy (HCM) were previously considered poor candidates for mechanical circulatory support due to technical limitations related to restrictive ventricular physiology and small ventricular size, limiting the ability to provide adequate flows and decompress the heart. Literature examining use of extracorporeal membrane oxygenation (ECMO) in this population consists of a single case series reporting no survivors. We report our experience providing ECMO in children with RCM or HCM at a large pediatric quaternary cardiac center.

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The highly contagious malaria disease is spread by the female Anopheles mosquito. This disease results in a patient's death or incapacity to move their muscles, if it is not appropriately identified in the early stages. A Rapid Diagnostic Test (RDT) is a frequently used approach to find malaria cells in red blood cells.

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Unlabelled: Data describing the use of extracorporeal membrane oxygenation (ECMO) in pediatric acute liver failure (PALF) are scarce. Thus, we aimed to describe the use of ECMO in patients with PALF using the data from the Extracorporeal Life Support Organization (ELSO) Registry between January 1, 2010, to December 31, 2022. We described patients' characteristics at ECMO initiation, outcome, and factors associated with mortality.

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Nutrition provision for children with heart disease supported with extracorporeal membrane oxygenation (ECMO) involves nuanced decision making. We examined nutrition provision while on ECMO in the CICU and the relationship between energy and protein adequacy and end organ function as assessed by pediatric sequential organ failure assessment (pSOFA) scores in children with heart disease supported with ECMO. Children (≤ 21 years-old) with congenital or acquired heart disease who received ECMO in the cardiac intensive care unit were included.

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Article Synopsis
  • A study was conducted to evaluate the trends in the use of extracorporeal cardiopulmonary resuscitation (ECPR) in children with cardiac disease following in-hospital cardiac arrest, as existing epidemiological data were insufficient.
  • Researchers analyzed data from nine observational studies involving 17,669 pediatric patients, with findings indicating that 21% of these patients received ECPR during their resuscitation efforts.
  • Meta-regression analysis showed a significant increase in ECPR usage over time among critically ill children with cardiac disease, suggesting improved adoption of this life-saving intervention.
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