Sex differences and frequency content of the Frank lead signal-averaged ECG in a normal population.

To quantify the content of the signal-averaged electrocardiogram (ECG) in normal subjects, 100-beat signal-averaged Frank lead ECGs at a sampling rate of 1,000 Hz and with 16-bit resolution were recorded from 88 women and 102 men with a combined average age of 22 years. The QRS portion of each lead was digitally filtered in four bandwidths: 0-10, 10-60, 60-150, and 150-250 Hz. The root-mean-square voltage of each filtered signal was calculated as an absolute value and normalized as a percentage of the sum of the four filters.

Prophylaxis against the systemic hypotension induced by propofol during rapid-sequence intubation.

The objective of this study was to determine the effectiveness of two prophylactic approaches against the anticipated hypotension induced by propofol during rapid-sequence intubation. Thirty-six male or female nonpremedicated ASA class I-II patients aged 21-60 yr undergoing elective outpatient surgery were included in the study. Patients were randomly allocated to receive pre-induction ephedrine sulphate (70 micrograms x kg(-1)iv), pre-induction volume loading (12 ml x kg(-1) Ringer's lactate) or no treatment.

Frequency content and sex difference of the Frank lead signal-averaged ECG in a population with significant coronary artery disease. Comparison with concurrent 12-lead ECG morphology.

The 12-lead electrocardiogram (ECG) and a 100-beat signal-averaged Frank lead ECG (SAECG) at a sampling rate of 1,000 Hz and with 16-bit resolution were recorded from 52 women and 256 men with significant coronary artery disease presenting for coronary artery revascularization. The QRS portion of each Frank lead was digitally filtered in four bandwidths: 0-10, 10-60, 60-150, and 150-250 Hz. The root-mean-square (RMS) voltage of each filtered signal was calculated as an absolute value and normalized as a percentage of the sum of the four filters, creating 27 variables.

Early postoperative myocardial morbidity in patients with coronary artery disease undergoing major non-cardiac surgery: correlation with perioperative ischaemia.

As a part of a study assessing early postoperative myocardial morbidity in 50 patients with active coronary artery disease undergoing major non-cardiac surgery, the ECG was monitored continuously for 24 hr after the onset of anaesthesia, using a frequency modulated (FM) Holter monitor. Concurrent automated blood pressure and pulse were measured non-invasively at three-minute intervals during anaesthesia and subsequently at five-minute intervals. Thirty patients were monitored with two-site ECG recordings, from modified V1 and V5 (Group A).