Publications by authors named "R D Sacks"
Background: Type 2 inflammation dominates eosinophilic chronic rhinosinusitis (eCRS) and adult onset asthma. IL-4, -5, and -13 are prominent disease mediators. Disease control can be achieved with biologic therapies.
View Article and Find Full Text PDFArticle Synopsis
- Radiomics involves extracting features from medical imaging data to enhance clinical applications, especially in rhinology where CT imaging of the paranasal sinus is crucial for diagnosis and treatment assessment.
- A systematic review analyzed techniques for radiomic data derived from CT scans, resulting in 10 eligible studies categorized into diagnostics and prognostics, using various extraction methods and analytical approaches.
- While the potential of radiomics in rhinology is promising, the current studies show variable quality and limited clinical applicability, indicating a need for more robust research in this area.
Endonasal Thermal Imaging Before and After Nasal Airway Surgery.
Ann Otol Rhinol Laryngol
January 2025
Objective: Nasal airway surgery is often applied when treatment fails to relieve nasal obstruction. However, surgery that improves airflow does not always alleviate the symptoms of nasal obstruction. The perception of nasal breathing is likely more related to changes in mucosal temperature than the mechanical sensation of flow or pressure.
View Article and Find Full Text PDFObjective: To assess the effect of allergen immunotherapy (AIT) on patients with central compartment atopic disease (CCAD) and house dust mite (HDM) sensitization post-surgery.
Methods: A retrospective cohort of surgically treated, HDM-sensitized CRSwNP patients phenotyped as CCAD was assessed. Patients were divided into two groups based on whether they had AIT commenced as part of their surgical care.