Publications by authors named "R D Ponder"

Article Synopsis
  • Chilaiditi syndrome occurs when the interpositioning of the colon between the liver and diaphragm leads to complications like respiratory issues or bowel obstruction.
  • A 70-year-old man with multiple health issues presented with symptoms including shoulder pain and dizziness, which were initially linked to dehydration.
  • Imaging revealed a Chilaiditi sign and possible bowel obstruction; despite treatment, his condition improved primarily with hydration and bowel rest, illustrating the complexities of managing this syndrome alongside other chronic conditions.
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Background And Aims: The presence of steatosis in a donor liver and its relation to post-transplantation outcomes are not well defined. This study evaluates the effect of the presence and severity of micro- and macro-steatosis of a donor graft on post-transplantation outcomes.

Methods: The UNOS-STAR registry (2005-2019) was used to select patients who received a liver transplant graft with hepatic steatosis.

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Background And Aim: In this study, we used a national cohort of patients with Wilson's disease (WD) to investigate the admissions, mortality rates, and costs over the captured period to assess specific subpopulations at higher burden.

Methods: Patients with WD were selected using 2016-2019 National Inpatient Sample (NIS). The weighted estimates and patient data were stratified using demographics and medical characteristics.

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Article Synopsis
  • This study explored the molecular mechanisms of Fontan-associated liver disease (FALD) by examining gene expression differences in liver fibrosis among patients.
  • Researchers analyzed data from 106 adults with the Fontan circulation, identifying upregulated genes in those with advanced fibrosis and assessing clinical outcomes.
  • Findings revealed that patients with advanced fibrosis had increased inflammation and vascular development gene activity, but these did not predict clinical outcomes like serious complications.
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Background And Aim: Autoimmune hepatitis (AIH) is a prominent cause of chronic liver disease in the United States. This study aims to characterize the incidence, mortality, and cost implications of this condition using a national database.

Method: The 2016-2019 National Inpatient Sample was used to select patients with AIH.

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