Publications by authors named "R D Kilpatrick"
Direct-acting antiviral (DAA) therapy is associated with a significant reduction in hepatocellular carcinoma (HCC) incidence among patients with cirrhosis, but data are conflicting about the risk of recurrence following DAA therapy. DAA-PASS was a prospective, pragmatic, observational study designed to estimate the risk of HCC recurrence associated with DAA therapy exposure during routine clinical care. Eligible patients were DAA treatment naive with Barcelona Clinic Liver Cancer (BCLC) stage A.
View Article and Find Full Text PDFImportance: Preterm infants are recommended to receive most vaccinations at the same postnatal age as term infants. Studies have inconsistently observed an increased risk for postvaccination apnea in preterm infants.
Objective: To compare the proportions of hospitalized preterm infants with apnea and other adverse events in the 48 hours after 2-month vaccinations vs after no vaccinations.
Article Synopsis
- - The study analyzed trends in gabapentin use among infants in neonatal intensive care units (NICUs) from 2005 to 2020, finding that only 85 infants (less than 0.01%) received the drug despite a significant increase of 1,055% in usage over that time.
- - Gabapentin-exposed infants had a lower median birth weight (2,160 g) compared to those who did not receive it (2,498 g), and many were premature or had chronic health issues such as lung disease and drug withdrawal syndrome.
- - The research highlighted concerns about the safety and effectiveness of gabapentin in infants, emphasizing the need for more studies to understand its implications better. *
Article Synopsis
- Acute and chronic pain caused by sickle cell disease (SCD) significantly impacts patients' quality of life and often requires ongoing medication for management.* -
- A project was launched to create a bedside mindfulness intervention aimed at improving self-efficacy in pain management for SCD patients experiencing vaso-occlusive episodes, utilizing feedback from both healthcare professionals and patients.* -
- Preliminary results indicated that participants found the mindfulness intervention helpful, reporting increased mindfulness and interest in tailored, non-pharmacological approaches to manage their pain and psychological stress.*